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Buy Now : medsshoppharma.org/product-category/buy-tramadol-online/ : When smaller dosages of this opioid painkiller are not enough to treat moderate to severe pain, doctors will prescribe 100 mg of the higher-strength drug, tramadol. via attaching to opioid receptors and preventing serotonin and norepinephrine from being reabsorbed, it improves pain management via acting on the central nervous system. This dosage is used for chronic disorders (arthritis, neuropathy) or acute pain (post-surgical), and it is usually available in immediate-release or extended-release forms.