I believe this is the first appearance of Mr. Danders after Cul de Sac went into daily syndication in 2007 (i.e., what we see here in GoComics.com). But Mr. Danders had appeared in the strip before.
So this seems like a good opportunity to point out some pre-syndication strips starring Mr. Danders that Richard Thompson rescued soon after he was forced to end the strip due to his illness:
I believe this is the first appearance of Mr. Danders after Cul de Sac went into daily syndication in 2007 (i.e., what we see here in GoComics.com). But Mr. Danders had appeared in the strip before.
So this seems like a good opportunity to point out some pre-syndication strips starring Mr. Danders that Richard Thompson rescued soon after he was forced to end the strip due to his illness:
http://richardspooralmanac.blogspot.nl/2013/04/the-lost-unintentional-adventures-of.html